
Dr. Phillip Fleshner has dedicated over 25 years to the field of colorectal surgery, combining clinical expertise with extensive research contributions. He has treated patients with colorectal disease surgically throughout his career and has authored over 100 peer-reviewed papers on various aspects of colorectal surgery. His research primarily focuses on multidisciplinary approaches to perioperative care, investigating clinical and subclinical factors impacting surgical outcomes.
Dr. Fleshner's research extends to inflammatory bowel diseases, particularly Crohn’s disease and ulcerative colitis, where he studies phenotypic subgroups and their correlation with surgical outcomes. His findings inform pre- and post-operative protocols aimed at optimizing outcomes for these conditions. He also explores the effects of perioperative immune suppression on surgical outcomes in IBD patients.
Known for challenging conventional practices, Dr. Fleshner has reshaped perioperative care strategies, particularly in the use of steroids, heparin prophylaxis, and early postoperative oral intake following major intra-abdominal surgery. Currently, he holds the Shierley, Jesslyne, and Emmeline Widjaja Chair in Colorectal Surgery at CSMC and serves as Clinical Professor of Surgery at the UCLA School of Medicine, where he continues to advance the field through innovative research and patient care.
Selected publications from PubMed
Upfront medical or surgical treatment in Crohn's disease.
Noor NM, Fleshner PR, Melmed GY, Siegel CA
Lancet Gastroenterol Hepatol. 2026 Jul;11(7):551-552 doi: 10.1016/S2468-1253(26)00078-6.
Artificial intelligence performance in generating colorectal surgery board questions.
Zuo J, Marty M, Maniskas S, Akopian G, Zaghiyan K, Fleshner P, Truong A
Am J Surg. 2026 Jul;257:116860 doi: 10.1016/j.amjsurg.2026.116860.
Darvadstrocel in Patients With Crohn's Disease With Complex Perianal Fistulas: The ADMIRE CD II Phase 3 Randomized Trial.
Colombel JF, Garcia Olmo D, Chen ST, Serclova Z, Schwartz DA, Wexner SD, Panés J, Wu C, Zhang B, Song M, McKay C, Nazarey P, Wright E, Raffals L, Fleshner P
Gastroenterology. 2026 Jun;170(7):1562-1570 doi: 10.1053/j.gastro.2025.12.033.
Intestinal Ultrasound for Monitoring Postoperative Crohn's Disease: A Review and Visual Atlas.
Gu P, Karime C, Fleshner P, Falloon K, Qazi T, Ernest-Suarez K, Pabla B, St-Pierre J, Melmed GY, Damas OM, Huynh HQ, Lu C, Kellar A, Intestinal Ultrasound Group of the United States and Canada (iUSCAN)
Inflamm Bowel Dis. 2026 Apr 1;32(4):755-764 doi: 10.1093/ibd/izaf248.
AVB-114 Demonstrates Clinical Benefit in Persistent Crohn's Perianal Fistulas: Randomized Cohort Results From the Multicenter STOMP2 Trial.
Schwartz DA, Dozois E, Ehman E, Faubion W Jr, Hudesman D, Johnson T, Pabla B, Papadakis K, Fleshner P
Am J Gastroenterol. 2026 Mar 25 doi: 10.14309/ajg.0000000000004005.
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